IISc Study Uncovers Cancer Cell Adaptation During Migration
IISc Bangalore’s recent study, published in Biophysical Journal, explores how ovarian cancer cells adapt their movement in various environments. Researchers observed two cell types, OVCAR-3 (rounded) and SK-OV-3 (elongated), on surfaces mimicking healthy and scarred tissues. OVCAR-3 cells exhibited a unique “slipping” movement on stiff surfaces, suggesting complex environmental interactions. These insights advance understanding of metastasis, especially in ovarian cancer, and may guide future treatment strategies, particularly using 3D modeling to study cell behaviour.
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